NHC-catalysed diastereoselective synthesis of multifunctionalised piperidines via cascade reaction of enals with azalactones.
نویسندگان
چکیده
NHC-catalysed azalactone ring-opening and piperidine ring-closing cascade with α,β-unsaturated aldehydes (enals) in a one-pot operation is reported. The present reaction cascade offers a convenient method for a highly diastereoselective synthesis of multifunctionalised piperidines in excellent yields under mild conditions.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 48 31 شماره
صفحات -
تاریخ انتشار 2012